All Categories (1-3 of 3)

1. Continuous purification of active pharmaceutical ingredients using multistage organic solvent nanofiltration membrane cascade

   out of 5 stars 

   Contributor(s):: Peeva, L, Burgal, JDValtcheva, I, Livingston, AG

   Downstream processing accounts for a large fraction of the production costs in pharmaceutical manufacturing. Organic solvent nanofiltration performed in a membrane cascade offers an interesting possibility for a continuous downstream processing unit operation. This work demonstrates continuous...

2. Continuous Crystallization with Impurity Complexation and Nanofiltration Recycle

   out of 5 stars 

   Contributor(s):: Vartak, S, Myerson, AS

   For crystal-impurity systems with similar structures and molecular weights, the impurity has a strong tendency to incorporate into the crystal lattice, making it difficult to obtain high purity with a single crystallization or even multiple crystallizations. In such cases, complexation of the...

3. Construction of ultrathin PTMSP/Porous nanoadditives membranes for highly efficient organic solvent nanofiltration (OSN)

   out of 5 stars 

   Contributor(s):: Liu, Q, Smith, SJDKonstas, K, Ng, D, Zhang, KS, Hill, MR, Xie, ZL

   Organic solvent nanofiltration (OSN), also known as solvent resistant nanofiltration (SRNF), has enormous potential for industrial applications. Among the emerging high-performance membrane materials, some have proven challenging to fabricate ultrathin selective layers and at a scale large enough...