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Tags: organocatalysis

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  1. Continuous Flow Intensification for the Synthesis of High-Purity Warfarin

    Contributor(s):: Silva-Brenes, Diana V., Reyes-Vargas, Stephanie K., Duconge, Jorge, Vlaar, Cornelis, Stelzer, Torsten, Monbaliu, Jean-Christophe M.

    While racemic warfarin was initially commercialized as a rodenticide, it has become the most prescribed anticoagulant drug for prevention of blood clots and is part of the World Health Organization’s list of essential medicines. The synthesis of warfarin appears straightforward, consisting of a...

  2. Flow Chemistry: Recent Developments in the Synthesis of Pharmaceutical Products

    Contributor(s):: Porta, R, Benaglia, M, Puglisi, A

    Recently, application of the flow technologies for the preparation of fine chemicals, such as natural products or Active Pharmaceutical Ingredients (APIs), has become very popular, especially in academia. Although pharma industry still relies on multipurpose batch or semibatch reactors, it is...