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1. Continuous flow asymmetric synthesis of chiral active pharmaceutical ingredients and their advanced intermediates

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   09 Jun 2023 | Contributor(s):: Otvos, SB, Kappe, CO

   Catalytic enantioselective transformations provide well-established and direct access to stereogenic synthons that are broadly distributed among active pharmaceutical ingredients (APIs). These reactions have been demonstrated to benefit considerably from the merits of continuous processing and...