The effects of unintentional and intentional process disturbances on tablet quality during long continuous manufacturing runs
Contributor(s):: Taipale-Kovalainen, Krista, Karttunen, Anssi-Pekka, Niinikoski, Hannes, Ketolainen, Jarkko, Korhonen, Ossi
Several kinds of process disturbances can occur during (continuous) tablet manufacturing, i.e. unintentional or intentional disturbances. Long run-time continuous manufacturing studies are used to investigate the effects of intentional and unintentional deviations. In this study, the horizontal...
Effect of force feeder on tablet strength during compression
Contributor(s):: Narang, Ajit S., Rao, Venkatramana M., Guo, Hang, Lu, Jian, Desai, Divyakant S.
Mechanical strength of tablets is an important quality attribute, which depends on both formulation and process. In this study, the effect of process variables during compression on tablet tensile strength and tabletability (the ratio of tensile strength to compression pressure) was investigated...