Enabling precision manufacturing of active pharmaceutical ingredients: workflow for seeded cooling continuous crystallisations
09 Jun 2023 | Contributor(s):: Brown, CJ, McGlone, TYerdelen, S, Srirambhatla, V, Mabbott, F, Gurung, R, Briuglia, ML, Ahmed, B, Polyzois, H, McGinty, J, Perciballi, F, Fysikopoulos, D, MacFhionnghaile, P, Siddique, H, Raval, V, Harrington, TS, Vassileiou, AD, Robertson, M, Prasad, E, Johnston, A, Johnston, B, Nordon, A, Srai, JS, Halbert, G, ter, Horst, JH, Price, CJ, Rielly, CD, Sefcik, J, Florence, AJ
Continuous manufacturing is widely used for the production of commodity products. Currently, it is attracting increasing interest from the pharmaceutical industry and regulatory agencies as a means to provide a consistent supply of medicines. Crystallisation is a key operation in the isolation of...