Characteristics of residence time distribution in a continuous high shear mixer granulation using scraper rotation
Contributor(s):: Tomita, Yosuke, Takeuchi, Yoshiko, Natsuyama, Susumu, Takeuchi, Hirofumi
Characteristics of residence time distribution (RTD) in a continuous high shear mixer granulation were investigated to promote the development of a continuous manufacturing process in the pharmaceutical industry. A continuous granulator with an impeller and a scraper was utilized. The tracer...