All Categories (1-2 of 2)

1. Selective preparation of elusive and alternative single component polymorphic solid forms through multi-component crystallisation routes

   0.0 out of 5 stars 

   09 Jun 2023 | Contributor(s):: Thomas, LH, Wales, C, Wilson, CC

   A transferable, simple, method for producing previously elusive and novel polymorphic forms of important active pharmaceutical ingredients (APIs; paracetamol (acetaminophen), piroxicam and piracetam) is demonstrated. Nitrogen heterocyclic co-molecules are employed to influence the self-assembly...

2. Intermolecular hydrogen transfer and solubility tuning in multi-component molecular crystals of the API piroxicam

   0.0 out of 5 stars 

   09 Jun 2023 | Contributor(s):: Thomas, LH, Klapwijk, ARWales, C, Wilson, CC

   A series of twelve multi-component molecular crystals of the active pharmaceutical ingredient (API) piroxicam (PX) have been synthesised and their structures analysed with respect to their supramolecular motifs and degree of intermolecular hydrogen transfer observed on formation of the various...