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1. Anti-fouling control of plug-flow crystallization via heating and cooling cycle

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   09 Jun 2023 | Contributor(s):: Koswara, Andy, Nagy, Zoltan K.

   Plug-flow crystallization (PFC) is a promising continuous pharmaceutical crystallization process but is prone to fouling due to uncontrolled crystallization on the reactor surface (encrustation). This results in operational issues such as (1) flow blockage, (2) increased thermal resistance, and...