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1. Prediction of tablet weight variability in continuous manufacturing

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   09 Jun 2023 | Contributor(s):: Razavi, Sonia M., Scicolone, James, Snee, Ronald D., Kumar, Ashish, Bertels, Johny, Cappuyns, Philippe, Van Assche, Ivo, Cuitino, Alberto M, Muzzio, Fernando

   This paper provides a method for prediction of weight variability of tablets made in rotary tablet presses as a function of material attributes and processing parameters. The goal was to be able to predict whether or not a formulation is suitable for direct compaction continuous manufacturing...

2. Influence of process parameters and equipment on dry foam formulation properties using indomethacin as model drug

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   09 Jun 2023 | Contributor(s):: Sprunk, A, Page, S, Kleinebudde, P

   Dry foam technology was developed to overcome insufficient oral bioavailability of poorly soluble and wettable active pharmaceutical ingredients (APIs). It is intended to enable a faster and more efficient dissolution by avoiding API agglomeration and floating of non-wetted API particles. The aim...

3. Implementation of an online thermal imaging to study the effect of process parameters of roller compactor

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   09 Jun 2023 | Contributor(s):: Omar, Chalak S., Hounslow, Michael J., Salman, Agba D.

   During roller compaction, not only the properties of the primary powder affect the product quality but also the process parameters. Any change in the process parameters during roller compaction will result in changing the properties of the ribbon. In this study, the temperature of the ribbon...