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Tags: Quantitative analysis

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  1. Real-Time Monitoring of Powder Mixing in a Convective Blender Using Non-Invasive Reflectance NIR Spectrometry

    out of 5 stars 

    Contributor(s):: Bellamy, L. J., Littlejohn, D., Nordon, A.

    A convective blender based on a scaled down version of a high shear mixer-granulator was used to produce binary mixtures of microcrystalline cellulose (Avicel) and aspirin, citric acid, aspartame or povidone. Spectra of stationary Avicel or aspirin powder provided an indication of the information...

  2. Detailed Analysis of the Online Near-Infrared Spectra of Pharmaceutical Blend in a Rotary Tablet Press Feed Frame

    out of 5 stars 

    Contributor(s):: Šašić, Slobodan, Blackwood, Daniel, Liu, Angela, Ward, Howard W, Clarke, Hugh

    The present study is an in-depth analysis of the online near-infrared (NIR) spectra acquired with a spectrometer mounted on the rotary tablet press feed frame. A 3.5% active pharmaceutical ingredient (API) formulation is analyzed. An attempt is made to determine the API univariately via the 2nd...