Rapid On-Demand Synthesis of Lomustine under Continuous Flow Conditions
Contributor(s):: Jaman, Z, Sobreira, TJPMufti, A, Ferreira, CR, Cooks, RG, Thompson, DH
Lomustine, an important agent for treatment of brain tumors and Hodgkin's lymphoma, has been synthesized using continuous flow methodology. Desorption electrospray ionization mass spectrometry (DESI-MS) was used to quickly explore a large number of reaction conditions for one of the reaction...