Monitoring blend potency in a tablet press feed frame using near infrared spectroscopy
Contributor(s):: Ward, Howard, Blackwood, Daniel, Polizzi, Mark, Clarke, Hugh
A near-infrared (NIR) probe was installed into the feed frame of a rotary tablet press to monitor API concentration as a function of time. A series of step change experimental trials were completed, where a placebo blend was initially charged into the feed frame, and an active blend was layered...
Deep UV Raman and fluorescence spectroscopy for real-time in situ process monitoring
Contributor(s):: Hug, WF, Nguyen, QReid, M, Sijapati, K, Reid, RD
Raman spectroscopy has become an increasingly common analytical method for real-time, on-line, in-line, and off-line in situ monitoring of product quality in a variety of pharmaceutical, chemical, and biological manufacturing environments, including wastewater quality [1]. The major shortcomings...