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Tags: Repeatability

Resources (1-2 of 2)

  1. Use of a continuous twin screw granulation and drying system during formulation development and process optimization

    09 Jun 2023 | Contributor(s):: Vercruysse, J., Peeters, E., Fonteyne, M., Cappuyns, P., Delaet, U., Van Assche, I., De Beer, T., Remon, J. P., Vervaet, C.

    Since small scale is key for successful introduction of continuous techniques in the pharmaceutical industry to allow its use during formulation development and process optimization, it is essential to determine whether the product quality is similar when small quantities of materials are...

  2. Stability and repeatability of a continuous twin screw granulation and drying system

    09 Jun 2023 | Contributor(s):: Vercruysse, J., Delaet, U., Van Assche, I., Cappuyns, P., Arata, F., Caporicci, G., De Beer, T., Remon, J. P., Vervaet, C.

    The aim of this study was to investigate the process transfer of a commercially available product from the current batch fluid bed granulation and drying production method to an innovative continuously operating from powder to tablet production line using twin screw granulation as an intermediate...