Practical application of roller compaction process modeling
09 Jun 2023 | Contributor(s):: Reynolds, Gavin, Ingale, Rohit Roberts, Ron Kothari, Sanjeev, Gururajan, Bindhu
Very limited work has been reported on comparing the performance of the roller compaction process at different scales. The majority of the approaches highlighted in the literature discuss the applicability of using confined uniaxial compaction for predicting the performance of the roller...
Laser triangulation as a fast and reliable method for determining ribbon solid fraction; focus on accuracy, precision, and measurement time
09 Jun 2023 | Contributor(s):: Lillotte, Tim D, Bebernik, Paul, Keck, Johanna, Bommer, Moritz, Schroeder, Daniela, Wagner, Karl G.
Roller compaction and dry granulation represent well-established unit operations in the pharmaceutical industry. The ribbon solid fraction is classified as a critical quality attribute, that directly impacts final product quality and performance. The development and evaluation of novel methods...