Resources (1-2 of 2)

1. Experimental determination of residence time distribution in continuous dry granulation

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   Contributor(s):: Mangal, Haress, Kleinebudde, Peter

   With increasing importance of continuous manufacturing, the interest in integrating dry granulation into a continuous manufacturing line is growing. Residence time distribution measurements are of importance as they provide information about duration of materials within the process. These data...

2. A quality by design approach to investigate the effect of mannitol and dicalcium phosphate qualities on roll compaction

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   Contributor(s):: Souihi, Nabil, Dumarey, Melanie, Wikstrom, Hakan, Tajarobi, Pirjo, Fransson, Magnus, Svensson, Olof, Josefson, Mats, Trygg, Johan

   Roll compaction is a continuous process for solid dosage form manufacturing increasingly popular within pharmaceutical industry. Although roll compaction has become an established technique for dry granulation, the influence of material properties is still not fully understood. In this study, a...