Computer Aided Design of Solvent Blends for Hybrid Cooling and Antisolvent Crystallization of Active Pharmaceutical Ingredients
Contributor(s):: Watson, OL, Jonuzaj, SMcGinty, J, Sefcik, J, Galindo, A, Jackson, G, Adjiman, CS
Choosing a solvent and an antisolvent for a new crystallization process is challenging due to the sheer number of possible solvent mixtures and the impact of solvent composition and crystallization temperature on process performance. To facilitate this choice, we present a general computer aided...