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Tags: scale-up synthesis

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  1. Scale-Up of a Continuous Manufacturing Process of Edaravone

    10 May 2024 | Contributor(s):: Zhou, Shuhao, Hong, Qingxia, Mei, Wenliu, He, Yan, Wu, Chengjun, Sun, Tiemin

    Edaravone belongs to a class of brain-protective agents, which can scavenge free radicals. To reduce impurities and improve the yield, a continuous flow production process of edaravone was developed. The synthesis is continuously carried out in two steps. The throughput can reach 11.328 kg/day...