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1. Wet Granulation in a Twin-Screw Extruder: Implications of Screw Design

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   09 Jun 2023 | Contributor(s):: Thompson, M. R., Sun, J.

   Wet granulation in twin-screw extrusion machinery is an attractive technology for the continuous processing of pharmaceuticals. The performance of this machinery is integrally tied to its screw design yet little fundamental knowledge exists in this emerging field for granulation to intelligently...

2. Hot-Melt Extrusion: from Theory to Application in Pharmaceutical Formulation

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   09 Jun 2023 | Contributor(s):: Patil, H, Tiwari, RV, Repka, MA

   Hot-melt extrusion (HME) is a promising technology for the production of new chemical entities in the developmental pipeline and for improving products already on the market. In drug discovery and development, industry estimates that more than 50% of active pharmaceutical ingredients currently...