All Categories (1-3 of 3)

1. Increasing Processing Flexibility to Meet Demand

   0.0 out of 5 stars 

   Magazine | 18 Nov 2024 | Contributor(s):: Felicity Thomas

   Evolving industry demands are driving the need for greater flexibility and innovation in processing equipment for pharmaceutical manufacturing.

2. Demonstrating scalability between two blender types using DEM

   0.0 out of 5 stars 

   Peer-reviewed journal | 12 Nov 2024 | Contributor(s):: Peter Boehling, Johan Remmelgas, Mohammadsadegh Salehi, Johannes Poms, Rúben Martins Fraga, Manel Bautista, Johannes G. Khinast, Emmanuela Gavi, Michela Beretta

   Powder blending is a critical step in pharmaceutical manufacturing that can impact product quality such as tablet tensile strength. This study utilized the Discrete Element Method (DEM) to investigate blending in a 5-liter mini-batch and a 2-liter Turbula blender. DEM parameters were calibrated...

3. A Concise Flow Synthesis of Efavirenz

   0.0 out of 5 stars 

   Peer-reviewed journal | 10 May 2024 | Contributor(s):: Correia, Camille A., Gilmore, Kerry, McQuade, D. Tyler, Seeberger, Peter H.

   Efavirenz is an essential medicine for the treatment of HIV, which is still inaccessible to millions of people worldwide. A novel, semi-continuous process provides rac-Efavirenz with an overall yield of 45 %. This streamlined proof-of-principle synthesis relies on the efficient copper-catalyzed...