Integrating sensors for monitoring blend content in a pharmaceutical continuous manufacturing plant
09 Jun 2023 | Contributor(s):: Panikar, Savitha, Li, Jingzhe, Rane, Varsha, Gillam, Sean, Callegari, Gerardo, Kurtyka, Bogdan, Lee, Sau, Muzzio, Fernando
In a pharmaceutical manufacturing process, Critical Quality Attributes (CQAs) need to be monitored not only for the final product but also for intermediates. Blend uniformity of powders is one such attribute that needs to be measured to ensure the quality of the final product. Multiple in-line...
An ontological knowledge-based system for the selection of process monitoring and analysis tools
09 Jun 2023 | Contributor(s):: Singh, Ravendra, Gernaey, Krist V, Gani, Rafiqul
Efficient process monitoring and analysis tools provide the means for automated supervision and control of manufacturing plants and therefore play an important role in plant safety, process control and assurance of end product quality. The availability of a large number of different process...