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  1. Inverse Method-Based Kinetic Modelling and Process Optimization of Reverse-Phase Chromatography for Molnupiravir Synthesis

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    | Contributor(s):: Fernando Muzzio, George Tsilomelekis, Ravendra Singh, Athanasios Kritikos

    Our research addresses the shift towards continuous manufacturing in the pharmaceutical industry, focusing on optimizing chromatographic separation for the synthesis of molnupiravir. Using an inverse method with six different inlet concentrations for a single objective function, we...

  2. Enabling intensification of multiphase chemical processes with additive manufacturing

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    | Contributor(s):: McMillin, RE, Luxon, AR, Ferri, JK

    Fixed bed supports of various materials (metal, ceramic, polymer) and geometries are used to enhance the performance of many unit operations in chemical processes. Consider first metal and ceramic monolith support structures, which are typically extruded. Extruded monoliths contain regular,...