Separation of Chemical Reaction Intermediates by Metal-Organic Frameworks
Contributor(s):: Centrone, A, Santiso, EE, Hatton, TA
HPLC columns custom-packed with metal-organic framework (MOF) materials are used for the separation of four small intermediates and byproducts found in the commercial synthesis of an important active pharmaceutical ingredient in methanol. In particular, two closely related amines can be separated...