The Use of Molecular Oxygen in Pharmaceutical Manufacturing: Is Flow the Way to Go?
Contributor(s):: Hone, CA, Roberge, DM, Kappe, CO
Molecular oxygen is arguably the greenest reagent available to the organic chemist. Most commonly, a diluted form of oxygen gas, consisting of less than 10% O-2 in N-2 ("synthetic air"), is used in pharmaceutical and fine chemical batch manufacturing to effectively address safety concerns when...