Peer-reviewed journal (1-3 of 3)

1. Real-time monitoring of the moisture content of filter cakes in vacuum filters by a novel soft sensor

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   09 Jun 2023 | Contributor(s):: Huttunen, Manu, Nygren, Lauri Kinnarinen, Teemu Ekberg, Bjarne, Lindh, Tuomo, Karvonen, Vesa, Ahola, Jero, Häkkinen, Antti

   The moisture content of filter cakes is probably the most important characteristic that should be kept at a desired level in industrial cake filtration applications to maintain consistent product quality and minimize energy consumption. Most of the currently applied methods for contactless...

2. Control of three different continuous pharmaceutical manufacturing processes: Use of soft sensors

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   09 Jun 2023 | Contributor(s):: Rehrl, J, Karttunen, APNicolai, N, Hormann, T, Horn, M, Korhonen, O, Nopens, I, De, Beer, T, Khinast, JG

   One major advantage of continuous pharmaceutical manufacturing over traditional batch manufacturing is the possibility of enhanced in-process control, reducing out-of-specification and waste material by appropriate discharge strategies. The decision on material discharge can be based on the...

3. A hybrid NIR-soft sensor method for real time in-process control during continuous direct compression manufacturing operations

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   09 Jun 2023 | Contributor(s):: Cogoni, Giuseppe, Husain, Anas, Alam, Md Anik, Liu, Yang Angela, Kamyar, Reza

   Near Infrared (NIR) spectroscopy is commonly utilized for continuous manufacturing as Process Analytical Technology (PAT) tool. This paper focus on a continuous direct compression manufacturing process, in which an NIR PAT probe is integrated into the tablet press feed frame and into the tablet...