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  1. Systematic framework for implementation of material traceability into continuous pharmaceutical tablet manufacturing process

    Contributor(s):: Billups, Matthew, Singh, Ravendra

    Purpose: With the applications of more advanced manufacturing technologies being applied to the pharmaceutical industry, continuous processes are at the forefront of innovation. One area that is highly desired to be systematically investigated is material traceability in continuous manufacturing...

  2. ICAS-PAT: A software for design, analysis and validation of PAT systems

    Contributor(s):: Singh, Ravendra, Gernaey, Krist V, Gani, Rafiqul

    In chemicals based product manufacturing, as in pharmaceutical, food and agrochemical industries, efficient and consistent process monitoring and analysis systems (PAT systems) have a very important role. These PAT systems ensure that the chemicals based product is manufactured with the specified...

  3. A New Software Framework for Implementing Crystal Growth Models to Materials of Any Crystallographic Complexity

    Contributor(s):: Zhao, Yongsheng, Tilbury, Carl J. Landis, Steven Sun, Yuanyuan, Li, Jinjin, Zhu, Peng, Doherty, Michael F.

    To continue the realization of new therapeutics, a more diverse range of solid forms is being considered. Synthetic modalities are broadening beyond simple organic molecules to more complicated structures, including organic salts, cocrystals, and solvates. As in all crystalline applications,...