Peer-reviewed journal (1-2 of 2)

1. Hot-Melt Extrusion: from Theory to Application in Pharmaceutical Formulation

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   09 Jun 2023 | Contributor(s):: Patil, H, Tiwari, RV, Repka, MA

   Hot-melt extrusion (HME) is a promising technology for the production of new chemical entities in the developmental pipeline and for improving products already on the market. In drug discovery and development, industry estimates that more than 50% of active pharmaceutical ingredients currently...

2. Characterization of Amorphous Solid Dispersion of Pharmaceutical Compound with pH-Dependent Solubility Prepared by Continuous-Spray Granulator

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   09 Jun 2023 | Contributor(s):: Tanaka, R, Hattori, YHorie, Y, Kamada, H, Nagato, T, Otsuka, M

   A continuous-spray granulator (CTS-SGR) is a one-step granulation technology capable of using solutions or suspensions. The present Research Article objectives were, (1) to reduce the manufacturing operations for solid dosage formulations, (2) to make amorphous solid dispersion (ASD) granules...