Predictive Model-Based Process Start-Up in Pharmaceutical Continuous Granulation and Drying
Contributor(s):: Pauli, Victoria, Kleinebudde, Peter, Krumme, Markus
Continuous manufacturing (CM) is a promising strategy to achieve various benefits in the context of quality, flexibility, safety and cost in pharmaceutical production. One of the main technical challenges of CM is that the process needs to handle transient conditions such as the start-up phase...