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Tags: Tablet manufacturing

Peer-reviewed journal (1-3 of 3)

  1. Pharmaceutical application of multivariate modelling techniques: a review on the manufacturing of tablets

    Contributor(s):: Shi, Guolin, Lin, Longfei, Liu, Yuling, Chen, Gongsen, Luo, Yuting, Wu, Yanqiu, Li, Hui

    The tablet manufacturing process is a complex system, especially in continuous manufacturing (CM). It includes multiple unit operations, such as mixing, granulation, and tableting. In tablet manufacturing, critical quality attributes are influenced by multiple factorial relationships between...

  2. Blend Segregation in Tablets Manufacturing and Its Effect on Drug Content Uniformity-A Review

    Contributor(s):: Jakubowska, E, Ciepluch, N

    Content uniformity (CU) of the active pharmaceutical ingredient is a critical quality attribute of tablets as a dosage form, ensuring reproducible drug potency. Failure to meet the accepted uniformity in the final product may be caused either by suboptimal mixing and insufficient initial blend...

  3. A quality by design approach to investigate the effect of mannitol and dicalcium phosphate qualities on roll compaction

    Contributor(s):: Souihi, Nabil, Dumarey, Melanie, Wikstrom, Hakan, Tajarobi, Pirjo, Fransson, Magnus, Svensson, Olof, Josefson, Mats, Trygg, Johan

    Roll compaction is a continuous process for solid dosage form manufacturing increasingly popular within pharmaceutical industry. Although roll compaction has become an established technique for dry granulation, the influence of material properties is still not fully understood. In this study, a...