Analysis of the Effects of Process Parameters on Start-Up Operation in Continuous Wet Granulation
Contributor(s):: Matsunami, Kensaku, Ryckaert, Alexander, Peeters, Michiel, Badr, Sara, Sugiyama, Hirokazu, Nopens, Ingmar, De Beer, Thomas
Toward further implementation of continuous tablet manufacturing, one key issue is the time needed for start-up operation because it could lead to lower product yield and reduced economic performance. The behavior of the start-up operation is not well understood; moreover, the definition of the...