Drying capacity of a continuous vibrated fluid bed dryer – Statistical and mechanistic model development
Peer-reviewed journal | 14 Sep 2023 | Contributor(s):: Johan Remmelgas, Robin Meier, Andreas Altmeyer, Daniel Emanuele, Miika Jormanainen, Anne Juppo, Pirjo Tajarobi, Luis Martin de Juan, Håkan Wikström
The drying capacity of a continuous vibrated fluid bed dryer was studied using a DoE by varying microcrystalline cellulose content in the formulation, water amount in the twin-screw granulation, inlet air temperature, air flow rate and the acceleration of the horizontal fluid-bed....
Assessment of blending performance of pharmaceutical powder mixtures in a continuous mixer using Discrete Element Method (DEM)
Peer-reviewed journal | 09 Jun 2023 | Contributor(s):: Behjani, MA, Motlagh, YGBayly, AE, Hassanpour, A
This study proposes a new sample-independent mixing index, termed the Coefficient of Blending Performance (CBP), for monitoring the formation of undesired API (Active Pharmaceutical Ingredient) agglomerates in continuous mixing processes. The proposed index is examined for the blending of...