The reality of in-line tablet coating
Contributor(s):: Cahyadi, Christine, Chan, Lai Wah, Heng, Paul Wan Sia
The possibility of continuous processing in pharmaceutical tablet manufacturing is hampered by the viscoelastic recovery of tablets post-compaction. Compacted tablets are typically aged before coating to allow complete viscoelastic recovery so as to avoid subsequent coating defects. There has...
A Study on In-Line Tablet Coating-the Influence of Compaction and Coating on Tablet Dimensional Changes
Contributor(s):: Cahyadi, C., Tan, B. X., Chan, L. W., Heng, P. W. S.
Prior to coating, tablets are usually stored for a definite period to enable complete strain recovery and prevent subsequent volumetric expansion-related coating defects. In-line coating is defined as the coating of tablets immediately after compaction. In-line coating will be expected to improve...