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Have you had challenges with CM adhesion/cohesion? Experts are discussing this topic in the Oral Solid Dosage Group,, broken out into the following key areas: conveying, feeding, transfer hoppers, and transition pipes. Learn from their experience by reading the full conversation here: https://cmkc.usp.org/groups/oralsoliddose/forum/default-section/discussions/111
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  1. Ask the Advisory Board

    https://cmkc.usp.org/uncategorised/asktheadvisoryboard

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  1. Where do I go for documentation?

    Documentation can be found in HUBzero's documentation page.

    https://cmkc.usp.org/kb/misc/testarticle

  2. What are groups?

    Work together with your colleaguesCreate a group to organize your interactions. Group members can:Post content that only other group members are allowed to seeExport their content to other web...

    https://cmkc.usp.org/kb/groups/general

  3. Frequently Asked Questions

    What are tags? How do I create a new tag? How can I delete a tag? How can I remove a tag from a resource/group/my profile/etc? Is there a limit on the number of tags I can add to an item? Can I...

    https://cmkc.usp.org/kb/tags/faq

  4. Frequently Asked Questions

    What are resources?How do I upload a new resource?How can I delete a resource?Is there a limit on the number of resources I can submit?What are resources?Think of a hub as an empty library....

    https://cmkc.usp.org/kb/resources/faq

  5. Customize your dashboard page

    To change your dashboard page, simply click the Personalize button located in the upper-right corner of that page. The page will enter a customization mode where you may move modules around by...

    https://cmkc.usp.org/kb/tips/personalize

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Resources feed

  1. Non-destructive detection of disintegrant levels in compressed oral solid dosage forms

    0.0 out of 5 stars 

    Contributor(s):: Sultan, Tipu, Rozin, Enamul Hasan, Dave, Vivek S., Cetinkaya, Cetin

    Quality issues related to compressed oral solid dosage (OSD) forms, such as tablets, arise during the design, development, and production stages, despite established processes and robust production tools. One of the primary quality concerns is the disintegration properties and drug release...

  2. Machine learning framework for extracting micro-viscoelastic and micro-structural properties of compressed oral solid dosage forms

    0.0 out of 5 stars 

    Contributor(s):: Sultan, Tipu, Rozin, Enamul Hasan, Paul, Shubhajit, Tseng, Yin-Chao, Cetinkaya, Cetin

    A compressed pharmaceutical oral solid dosage (OSD) form is a strongly micro-viscoelastic material composite arranged as a network of agglomerated particles due to its constituent powders and their bonding and fractural mechanical properties. An OSD product's Critical Quality Attributes, such as...

  3. Machine learning modeling for ultrasonic quality attribute assessment of pharmaceutical tablets for continuous manufacturing and real-time release testing

    0.0 out of 5 stars 

    Contributor(s):: Sultan, Tipu, Rozin, Enamul Hasan, Paul, Shubhajit, Tseng, Yin-Chao, Dave, Vivek S., Cetinkaya, Cetin

    In in-process quality monitoring for Continuous Manufacturing (CM) and Critical Quality Attributes (CQA) assessment for Real-time Release (RTR) testing, ultrasonic characterization is a critical technology for its direct, non-invasive, rapid, and cost-effective nature. In quality evaluation with...

  4. Orodispersible films: Product transfer from lab-scale to continuous manufacturing

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    Contributor(s):: Thabet, Yasmin, Breitkreutz, Joerg

    Orodispersible films have been described as new beneficial dosage forms for special patient populations. Due to various production settings, different requirements on film formulations are required for non- continuous and continuous manufacturing. In this study, a continuous coating machine was...

  5. Optimization of Critical Quality Attributes in Tablet Film Coating and Design Space Determination Using Pilot-Scale Experimental Data

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    Contributor(s):: Liu, Huolong, Meyer, Robert, Flamm, Matthew, Wareham, Laura, Metzger, Matthew, Tantuccio, Anthony, Yoon, Seongkyu

    In this study, the novel high-speed tablet film coating process in the continuous manufacturing was investigated. The influence of key process variables (inlet air flow rate, inlet air temperature, and suspension spray rate) were investigated using a Box-Behnken experimental design method....

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