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USP's Third Technical Guide: In-vitro dissolution modeling

  1. Atul Dubey

    The Technical Guide on In-vitro Dissolution Modeling for Oral Solid Drug Product Continuous Manufacturing is available for download from Pharmaceutical Continuous Manufacturing: USP Technical Guide.

     

    This guide focuses on presenting the state-or-the-art in surrogate dissolution models that can help in developing real-time release strategies. It starts from the very basics of models such as Weibull and Noyes-Whitney and explains the process of developing a surrogate model for modeling in-vitro dissolution. This knowledge can help stakeholders take their first steps toward predictive dissolution methods!

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