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Solid forms of pharmaceuticals: Polymorphs, salts and cocrystals

By Sarma, B; Chen, JHsi, HY; Myerson, AS

View Resource (DOI)

Category

Peer-reviewed journal

Published on

Abstract

Control and selection of the properties of active pharmaceutical ingredients is a crucial part of the drug development process. One major part of this process is the selection of an appropriate solid form. This review will discuss three major types of crystalline solids, polymorphs, salts and cocrystals and processes used to develop and find these forms.

Journal

Korean Journal of Chemical Engineering. Volume 28, 2011, 315-322

DOI

10.1007/s11814-010-0520-0

Type of publication

Peer-reviewed journal

Affiliations

  • Massachusetts Institute of Technology (MIT) (MIT)
  • Novartis MIT Center for Continuous Manufacturing

Article Classification

Review article

Classification Areas

  • API

Tags

  1. API
  2. Cocrystals
  3. design
  4. Pharmaceutical Salts
  5. Polymorphs
  6. Review article
  7. Scale-up
  8. Screening
  9. Solid Forms