This manuscript provides the results of an in-depth survey assessment of the capabilities, experience, and perspectives on continuous processing in the pharmaceutical sector, with respondents from both pharmaceutical companies and Contract Manufacturing Organizations (CMOs). The survey includes staffing (personnel), chemistry, reaction platforms, postreaction processing, analytical, regulatory, and factors that influence the adoption of continuous manufacturing. The results of the survey demonstrate that the industry has been increasing, and will continue to increase, the portion of total manufacturing executed as continuous processes with a decrease in batch processing. In general, most of the experience with continuous processing on scale have been enabling reaction chemistry, while postprocessing and analytical remain in the very early stages of development and implementation.

• Pfizer Worldwide Research & Development
• Amgen Inc
• Eli Lilly & Co; Biogen Idec Inc; GlaxoSmithKline

• API

1. Active pharmaceutical ingredient
2. API
3. continuous process
4. contract manufacturing organization
5. contract Research Article organization
6. flow chemistry
7. flow process
8. outsourcing
9. Pharmaceutical
10. Research Article
11. survey
12. unit operations