Continuous manufacturing processes promise shorter manufacturing cycle times without the need for intermediate storage, sampling testing and release of intermediate process steps, and shorter product release times through the intelligent application of in-line and at-line testing strategies. For continuous processes, the general testing strategy is designed to decrease the probability of critical quality attribute (CQA) failure through control of critical material attributes (CMA) and critical process parameters (CPP).

• Pharmatech Associates

• PAT

1. CQA
2. critical material attributes (CMAs)
3. pat
4. PAT / RTRT / QbD