Continuous-flow synthesis of the anti-malaria drug artemisinin
Category
Published on CMKC
Abstract
Malaria is a serious global health issue. Artemisinin combination treatments are the first-line drugs, but supplies are limited because artemisinin is obtained solely by extraction from Artemisia annua. A continuous-flow process that converts dihydroartemisinic acid into artemisinin (see scheme) was shown to be an inexpensive and scalable process that can ensure a steady, affordable supply of artemisinin.
Journal
Angewandte Chemie International Edition. Volume 51, 2012, 1706-1709
DOI
10.1002/anie.201107446
Type of publication
Peer-reviewed journal
Affiliations
- Max-Planck Society
Article Classification
Research Article
Classification Areas
- API