Preparation of fluoxetine by multiple flow processing steps
Category
Published on
Abstract
Microflow technology is established as a modern and fashionable tool in synthetic organic chemistry, bringing great improvement and potential, on account of a series of advantages over flask methods. The study presented here focuses on the application of flow chemistry process in performing an efficient multiple step syntheses of (±)-fluoxetine as an alternative to conventional synthetic methods, and one of the few examples of total synthesis accomplished by flow technique.
Journal
Organic & Biomolecular Chemistry. Volume 9, 2011, 3854-3862
DOI
10.1039/C0OB00906G
Type of publication
Peer-reviewed journal
Affiliations
- Eli Lilly & Company
Article Classification
Research article
Classification Areas
- API