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Preparation of fluoxetine by multiple flow processing steps

By Ahmed-Omer, Batoul; Sanderson, Adam J.

Published on

Abstract

Microflow technology is established as a modern and fashionable tool in synthetic organic chemistry, bringing great improvement and potential, on account of a series of advantages over flask methods. The study presented here focuses on the application of flow chemistry process in performing an efficient multiple step syntheses of (±)-fluoxetine as an alternative to conventional synthetic methods, and one of the few examples of total synthesis accomplished by flow technique.

Journal

Organic & Biomolecular Chemistry. Volume 9, 2011, 3854-3862

DOI

10.1039/C0OB00906G

Type of publication

Peer-reviewed journal

Affiliations

  • Eli Lilly & Company

Article Classification

Research article

Classification Areas

  • API

Tags