This book covers key aspects of the continuous manufacturing of pharmaceuticals. The first part provides an overview of key chemical engineering principles and the current regulatory environment. The second covers existing technologies for manufacturing both small-molecule-based products and protein/peptide products. The following section is devoted to process analytical tools for continuously operating manufacturing environments. The final two sections treat the integration of several individual parts of processing into fully operating continuous process systems and summarize state-of-art approaches for innovative new manufacturing principles. 

• Merck & Co Inc
• Temple University

• Oral solid dose

1. continuous processing
2. melt granulation
3. oral solid dose
4. Research Article
5. taste masking
6. Twin-screw granulation