Effects of rotation rate, mixing angle, and cohesion in two continuous powder mixers-A statistical approach
Category
Published on CMKC
Abstract
In this paper we examine the effect of rotation rate, mixing angle, and cohesion on the powder residence time and the content uniformity of the blend exiting from two continuous powder mixers. In addition, differences in mixing performance between the two blenders are examined. Analysis of variance is used to determine significance of main effects and their interactions. The results show that the effect of powder cohesion is scale-dependent, having a significant effect in the larger mixer. The overall rotation rate was the least influential parameter in terms of content uniformity. The residence time is significantly affected by both rotation rate and mixing angle.
Journal
Powder Technology. Volume 194, 2009, 217-227
DOI
10.1016/j.powtec.2009.04.010
Type of publication
Peer-reviewed journal
Affiliations
- Rutgers State University
Article Classification
Research article
Classification Areas
- Oral solid dose