Particle Engineering of an Active Pharmaceutical Ingredient for Improved Micromeritic Properties
Contributor(s):: Sowa, M, Klapwijk, AROstendorf, M, Beckmann, W
A range of particle-engineering techniques were applied to modify unfavorable bulk solid properties of an active pharmaceutical ingredient (API), with the solid-state form of the compound remaining constant. The compound under investigation has been crystallized as needle-like particles, which...
Method Development and Validation of an Inline Process Analytical Technology Method for Blend Monitoring in the Tablet Feed Frame Using Raman Spectroscopy
Contributor(s):: Li, Y, Anderson, CADrennen, JK, Airiau, C, Igne, B
Inline process analytical technology sensors are the key elements to enable continuous manufacturing. They facilitate real-time monitoring of critical quality attributes of both intermediate materials and finished products. The aim of this study was to demonstrate method development and...