Seven-Step Continuous Flow Synthesis of Linezolid Without Intermediate Purification
Contributor(s):: Russel, M. Grace, Jamison, Timothy F.
Herein, the blockbuster antibacterial drug linezolid is synthesized from simple starting blocks by a convergent continuous flow sequence involving seven (7) chemical transformations. This is the highest total number of distinct reaction steps ever performed in continuous flow without conducting...