Skip to main content
Prepare for an exciting September! Each week, we'll examine the latest trends in PAT, offering fresh insights straight from recent conferences. Your perspective matters, so we encourage you to share your thoughts as well. Stay informed, stay engaged, and let's explore these cutting-edge developments together. https://bit.ly/3Xw0X7k
3.139.79.36

Tags: Blender

More tags

All Categories (1-5 of 5)

  1. Improvement of a pharmaceutical powder mixing process in a tote blender via DEM simulations

    out of 5 stars 

    | Contributor(s):: Benedict Benque, Luca Orefice, Thomas Forgber, Matthias Habeler, Beate Schmid, Johan Remmelgas, Johannes Khinast

    An industrial-scale pharmaceutical powder blending process was studied via discrete element method (DEM) simulations. A DEM model of two active pharmaceutical ingredient (API) components and a combined excipient component was calibrated by matching the simulated response in a dynamic angle of...

  2. A modified Kushner-Moore approach to characterising small-scale blender performance impact on tablet compaction

    out of 5 stars 

    | Contributor(s):: Hikaru G. Jolliffe, Martin Prostredny, Carlota Mendez Torrecillas, Ecaterina Bordos, Collette Tierney, Ebenezer Ojo, Richard Elkes, Gavin Reynolds, Yunfei Li Song, Bernhard Meir, Sara Fathollahi, John Robertson

    Continuous Direct Compaction (CDC) has emerged as a promising route towards producing solid dosage forms while reducing material, development time and energy consumption. Understanding the response of powder processing unit operations, especially blenders, is crucial. There is a substantial body...

  3. Continuous Manufacturing for Pharmaceutical Solid Dosage Forms (On-Demand)

    out of 5 stars 

    | Contributor(s):: Atul Dubey, Fernando Muzzio, Gerardo Callegari, Lucy L. Botros, Ravendra Singh, James Scicolone, Andres Roman, Sonia Modarres Razavi

    Course Description: This self-paced curriculum contains fourteen self-paced modules and three recordings of live virtual education on Pharmaceutical Continuous Manufacturing (PCM). Learners will have access to the following: A recording of the introductory session covering topics such as...

  4. Multi-dimensional population balance modeling and experimental validation of continuous powder mixing processes

    out of 5 stars 

    | Contributor(s):: Sen, Maitraye, Singh, Ravendra Vanarase, Aditya John, Joyce, Ramachandran, Rohit

    It has been recognized that the application of quality by design (QbD) to continuous processing in the pharmaceutical industry leads to better process control, improved product quality and mitigates scale-up issues (Schaber et al., 2011), whereby a component of QbD involves the development...

  5. Mathematical development and comparison of a hybrid PBM-DEM description of a continuous powder mixing process

    out of 5 stars 

    | Contributor(s):: Sen, Maitraye, Dubey, Atul Singh, Ravendra, Ramachandran, Rohit

    This paper describes the development of a multidimensional population balance model (PBM) which can account for the dynamics of a continuous powder mixing/blending process. The PBM can incorporate the important design and process conditions and determine their effects on the various critical...