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1. Continuous micro feeding and mixing of solid dosage forms under vibrational excitation

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   Peer-reviewed journal | 08 Oct 2024 | Contributor(s):: Haifeng Lu, Liang Zhang, Hui Du, Xiaolei Guo, Haifeng Liu

   Continuous manufacturing has intrigued many researchers in the pharmaceutical industry in the post-COVID-19 world. We experimentally studied the discharge characteristics of pharmaceutical excipients under vibrational excitation. The successful accurate dosing and filling of powders at fill...

2. Real-Time Quantification of Low-Dose Cohesive Formulations within a Sampling Interface for Flowing Powders

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   Peer-reviewed journal | 09 Jun 2023 | Contributor(s):: Sierra-Vega, Nobel. O., Romañach, Rodolfo J., Mendez, Rafael

   This study investigates the performance of a sampling interface for monitoring cohesive, flowing powder formulations with Hausner's Ratio and Carr's Index higher than 1.5 and 35%, respectively. The sampler device was operated in combination with near-infrared (NIR) spectroscopy to quantify...