Chapter Book (1-2 of 2)

1. Real-time feasible model-based crystal size and shape control of crystallization processes

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   09 Jun 2023 | Contributor(s):: Szilagyi, Botond, Nagy, Zoltan K.

   The simultaneous control of crystal size and shape is particularly important in fine chemical and pharmaceutical crystallization. These two quantities influence the dissolution rate and bioavailability of final drug products, and also contribute to the manufacturability and efficiency of...

2. Model Based Estimation of 2D Crystallization Kinetics From Concentration and CLD Measurements

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   09 Jun 2023 | Contributor(s):: Szilagyi, Botond, Borsos, Akos Simone, Elena Nagy, Zoltan K., Espuña, Antonio, Graells, Moisès, Puigjaner, Luis

   Due to the fact that crystal size and shape influence relevant macroscopic properties of solid particles, the understanding and control of these quantities have increasing importance in particulate science. Crystallization, the primary crystal formation and purification process, is usually...