Continuous-flow synthesis of the anti-malaria drug artemisinin
Contributor(s):: Lévesque, François, Seeberger, Peter H
Malaria is a serious global health issue. Artemisinin combination treatments are the first-line drugs, but supplies are limited because artemisinin is obtained solely by extraction from Artemisia annua. A continuous-flow process that converts dihydroartemisinic acid into artemisinin (see scheme)...