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1. Videometric mass flow control: A new method for real-time measurement and feedback control of powder micro-feeding based on image analysis

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   09 Jun 2023 | Contributor(s):: Madarasz, L, Kote, AGyurkes, M, Farkas, A, Hambalko, B, Pataki, H, Fulop, G, Marosi, G, Lengyel, L, Casian, T, Csorba, K, Nagy, ZK

   The present paper reports the first monitoring and control of ultra-low dose powder feeding using a camera image-based mass flow measurement system. Caffeine was fed via a single-screw microfeeder as a model active pharmaceutical ingredient (API). The mass, mass flow and sizes of the particles...

2. Comparative Study of a Novel Micro-feeder and Loss-in-weight Feeders

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   09 Jun 2023 | Contributor(s):: Sacher, S, Fathollahi, S, Khinast, JG

   Purpose Accurate and reliable feeding of small quantities of powder is crucial in many industries. It is particularly true in the case of pharmaceutical manufacturing. First, the exact dosage of highly potent active pharmaceutical ingredients (APIs) is essential. Second, due to the shift towards...

3. A solution for low-dose feeding in continuous pharmaceutical processes

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   09 Jun 2023 | Contributor(s):: Sacher, S, Heindl, NUrich, JAA, Kruisz, J, Khinast, JG

   Continuous feeding of small quantities of powder is increasingly applied in pharmaceutical manufacturing. With that regard, what is crucial is not only the feasibility, but also the accuracy and stability. To enable stable processing, low amounts of various agents, e.g., lubricants, can be used....