Flowsheet modeling of a continuous direct compression process
09 Jun 2023 | Contributor(s):: Yoon, Seongkyu, Galbraith, Shaun, Cha, Bumjoon, Liu, Huolong
Continuous manufacturing for the production of pharmaceutical products is emerging as a key technology due to the advantages it has over traditional batch manufacturing methods. Process systems engineering is critical in rolling out this technology within the industry since it allows for more...
Ensuring tablet quality via model-based control of a continuous direct compaction process
09 Jun 2023 | Contributor(s):: Kirchengast, M, Celikovic, SRehrl, J, Sacher, S, Kruisz, J, Khinast, J, Horn, M
Switching from batch to continuous pharmaceutical production offers several advantages, such as an increased productivity, a steady product quality, and decreased costs. This paper presents a control strategy for direct compaction on a continuous tablet production line consisting of two feeders,...