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  1. The Continuous-Flow Synthesis of Ibuprofen

    24 Apr 2024 | Contributor(s):: Bogdan, Andrew R., Poe, Sarah L, Kubis, Daniel C., Broadwater, Steven J., McQuade, D. Tyler

    Let relief flow forth! A three-step, continuous-flow synthesis of ibuprofen was accomplished using a simplified microreactor. By designing a synthesis in which excess reagents and byproducts are compatible with downstream reactions, no intermediate purification or isolation steps are required.